The patient may suffer from weakness, weight loss and malaise. Symptoms and signs caused by inflammation and ischemia of the affected organs. Each organ may be affected, with the exception of the lungs. Peripheral neuropathy, gastrointestinal, renal artery and osteoarticular pathologies are the most common.
Kidney involvement may be in glomeruli or renal blood vessels and can cause acute kidney injury and hypertension. The typical presentation on children's involvement in one or two organs, with constitutional symptoms and a diagnosis is often based on pathology.
Also in many cases, the applications they produce overlapping diagnosis, especially in patients with small vessel vaskulitis classic polyarteritis nodosa and. The investigation of certain highly suggestive vaskulitis and/or granuloma, such as skin biopsy or angiography.
The most common areas affected including nerve, liver, gastrointestinal tract, and joints can also affect kidney blood vessels that results in high blood pressure and kidney function damage.
Vaskulitis is a general term that refers to inflammation of the blood vessels. When blood vessels become inflamed, they can only react with a limited way. When inflamed, the blood vessels may be weak and stretch in size, which can lead to aneurysms, or become so thin that they broke out resulting in bleeding into the tissues.
Vaskulitis also can lead to narrowing of the arteries to the point of closing completely in order for the organs to be damaged from the loss of oxygen and nutrients are supplied by blood.
They may have symptoms related to the field of engagement such as pain in the muscles and/or joints, skin sores may appear as nodules or hard tender ulcers, abdominal pain or blood in the stool occurs as a result of the involvement of the intestinal tract, or shortness of breath or chest pain from diseases that affect the heart.
High blood pressure common in the pot and is usually due to decreased blood flow to vaskulitis kidneys can affect nerves and cause abnormal sensations, numbness or loss of strength. Evidence from laboratory studies strongly support that the immune system plays an important role in the pot, causing blood vessels and tissue inflammation and damage.
Arteriogram involves the injection of dye into the blood stream that allows the visualization of blood vessels and may indicate a narrowing of the blood vessel or aneurysm suggestive of vaskulitis. A biopsy of the affected area is often done to try to confirm the presence of vaskulitis in the network.
Biopsy and arteriograms only recommended for organ site where there are abnormal findings present with examination, laboratory tests, or other types of imaging studies.
There are a wide variety of immunosuppressive drugs are used in a pan, which each have their own individual side effects.
In rare cases, people who have no manifestations which affect the nervous system, liver, kidneys, intestinal tract or other features of severe disease might do well with corticosteroid therapy alone.
All immunosuppressive drugs can have side effects. Monitoring for side effects play an important role in preventing or minimizing the occurrence. Every drug has a unique side effect profile that forms the basis for the monitoring plans.